Hydrolysed collagen. What does the research say?

We hear a lot about the great properties of hydrolyzed collagen. Its distinguishing features include high absorbability, as well as a low likelihood of allergy. Is it worth drinking hydrolysed collagen and what do the research say about it?

Hydrolysed collagen:

Some products are simply fashionable, and we reach for them without much reflection – especially if influencers or celebrities recommend them. However, it is worth looking a little deeper and finding out whether the effect of a given supplement has been supported by research. We took a closer look at hydrolysed collagen to see what it can really do in terms of health and beauty.

To begin with, we referred to an article published at the end of 2019 in Molecules – a scientific journal publishing research in the field of organic chemistry and chemistry of natural products.

Researchers indicate the existence of at least 28 types of collagen, of which type I collagen is most often found in the skin, bones, teeth, tendons and ligaments, type II collagen – in cartilage, and type III is found in the skin, muscles and blood vessels. It plays a structural role for tissues, which translates, among others, into on the strength of the skin and the tensile strength of ligaments.

When collagen is hydrolysed, the bonds in the polypeptide chain are broken. As a result, we obtain collagen peptides with low molecular weight. Thanks to this, hydrolysed collagen is distinguished by high bioavailability and is easily distributed in the human body. It can be used in the cosmetics, pharmaceutical and food industries and as an ingredient in nutraceuticals.

Why is it worth drinking hydrolysed collagen?

Oral collagen supplementation is associated with its loss in the human body. Scientists emphasise that the reduced production of this protein begins in the age range of 18-29, and in 80-year-olds, a decrease in collagen production by as much as 75% was observed and compared to young people.

What Slows Collagen Production In The Body? The article lists the following factors:

  • bad diet
  • free radicals
  • smoking tobacco
  • alcohol consumption
  • diseases

Meanwhile, the role of collagen in the body is difficult to overestimate. It supports the development of organs, heals wounds, affects the cornea and gums, builds bones, ligaments, tendons, muscles, skin and hair.

Reducing the amount of collagen contributes to the formation of wrinkles, but – good news here – hydrolysed collagen counteracts the deterioration of the skin, can retain water, and improves firmness and elasticity.

Oral collagen supplementation – research

Researchers also refer to other studies confirming the effectiveness of oral supplementation with hydrolysed collagen, including for work:

  • Asserin J., Lati E., Shioya T., Prawitt J., The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: Evidence from an ex vivo model and randomised, placebo-controlled clinical trials. J. Cosmet. Dermatol. 2015; 14: 291–301
  • Kim D.-U., Chung H.-C., Choi J., Sakai Y., Lee B.-Y., Oral intake of low-molecular-weight collagen peptide improves hydration, elasticity, and wrinkling in human skin: A randomised, double-blind, placebo-controlled study. Nutrients. 2018.

What follows from them? In vivo studies in women, 40 to 60 years of age who took oral hydrolysed collagen supplements for 12 weeks showed significant improvements in skin hydration, wrinkles and elasticity. The studies also showed a protective effect on the joints.

Hydrolysed collagen and joint diseases and osteoporosis

The action of hydrolysed collagen in the context of joint diseases was also developed by R. W. Moskowitz (Role of collagen hydrolysate in bone and joint disease). Referring to German, English and American studies in which patients were given collagen hydrolysates or a placebo, he concluded that taking the hydrolyzate may be used to treat osteoarthritis and osteoporosis. He also noted its high security. As you know, people suffering from ailments with joints should supplement with them for a long time, so the preparations dedicated to them cannot cause serious side effects.

  1. Arely León-López, Alejandro Morales-Peñaloza, Víctor Manuel Martínez-Juárez, Apolonio Vargas-Torres, Dimitrios I. Zeugolis and Gabriel Aguirre-Álvarez, Hydrolyzed Collagen—Sources and Applications, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891674/
  2. R. W. Moskowitz, Role of collagen hydrolysate in bone and joint disease, https://pubmed.ncbi.nlm.nih.gov/11071580/

Do you want to know more about collagen? Also read:

Collagen – supplementation that affects joints, skin, hair and nails!